Dickkopf genes are co-ordinately expressed in mesodermal lineages

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Dickkopf genes are co-ordinately expressed in mesodermal lineages

Dickkopf-1 (dkk-1) is member of a novel family of secreted proteins and functions in head induction during Xenopus embryogenesis, acting as a potent inhibitor of Wnt signalling. Here we report: (1) the isolation of two additional murine members of the dkk family, dkk-2 and dkk-3; and (2) analysis of adult and embryonic gene expression of mouse dkk-1,-2, and -3, Xenopus dkk-1 as well as chicken ...

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ژورنال

عنوان ژورنال: Mechanisms of Development

سال: 1999

ISSN: 0925-4773

DOI: 10.1016/s0925-4773(99)00138-0